Just Plain Bill was a long run 15-minute daytime radio drama program heard on CBS and NBC. The series was sponsored by Anacin for 18 of the program's 23-year run. Other sponsors over the years were Kolynos toothpaste, Clapp’s baby food and BiSoDol. It was “the real-life story of people just like people we all know.” Originally called Bill the Barber, the program began on CBS September 19, 1932. It told the story of Bill Davidson (Arthur Hughes), a barber in the town of Hartville, and his daughter Nancy (Ruth Russell). Bill often became involved in helping his friends and neighbors when he wasn't cutting hair.

The show was created by Frank and Anne Hummert, who produced many radio daytime drama series, including Amanda of Honeymoon Hill, Backstage Wife, Front Page Farrell, John’s Other Wife, Little Orphan Annie, Ma Perkins, Mr. Chameleon, Mr. Keen, Tracer of Lost Persons, Our Gal Sunday and Young Widder Brown.

Music was by Hal Brown. who played harmonica and whistled the Just Plain Bill opening theme, "Darling Nellie Gray". The closing theme was "Polly Wolly Doodle." Don Pardo was the program's announcer. The series came to an end in 1955.